STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NDRG1N-myc downstream regulated 1. (592 aa)    
Predicted Functional Partners:
ARHGEF10
Rho guanine nucleotide exchange factor 10.
   
  
 0.812
RAB3GAP1
RAB3 GTPase activating protein catalytic subunit 1.
   
  
 0.808
PBX4
PBX homeobox 4.
      
 0.674
SGK1
Non-specific serine/threonine protein kinase.
   
 
 0.616
PPME1
Protein phosphatase methylesterase 1; Demethylates proteins that have been reversibly carboxymethylated.
   
 
 0.582
RASSF7
Ras association domain family member 7.
   
  
 0.576
MYBBP1A
MYB binding protein 1a.
      
 0.568
VASH1
Vasohibin 1.
   
  
 0.566
SSR4
Signal sequence receptor subunit 4.
      
 0.560
BEX3
Brain expressed X-linked 3.
      
 0.560
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.