STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BTNL10Uncharacterized protein. (486 aa)    
Predicted Functional Partners:
ADAMTS16
ADAM metallopeptidase with thrombospondin type 1 motif 16.
      
 0.789
CTNND2
Catenin delta 2.
    
 
 0.784
CLCNKA
Chloride channel protein.
      
 0.529
UMOD
Uromodulin, secreted form; [Uromodulin]: Functions in biogenesis and organization of the apical membrane of epithelial cells of the thick ascending limb of Henle's loop (TALH), where it promotes formation of complex filamentous gel-like structure that may play a role in the water barrier permeability. May serve as a receptor for binding and endocytosis of cytokines (IL-1, IL-2) and TNF. Facilitates neutrophil migration across renal epithelia.
   
 
 0.511
CLCN4
Chloride channel protein.
      
 0.508
SIGLEC15
Sialic acid binding Ig like lectin 15.
    
 
 0.497
CLCN2
Chloride channel protein.
      
 0.487
CLCN3
Chloride channel protein.
      
 0.478
CLCN5
Chloride channel protein.
      
 0.469
CLCN7
Chloride channel protein.
      
 0.468
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: medium (52%) [HD]