STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NME5NME/NM23 family member 5; Belongs to the NDK family. (211 aa)    
Predicted Functional Partners:
AK1
Adenylate kinase isoenzyme 1; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
 
 
 0.760
CARD14
Caspase recruitment domain family member 14.
   
 0.745
DAW1
Dynein assembly factor with WD repeats 1.
   
  
 0.706
TTC25
Tetratricopeptide repeat domain 25.
   
 0.671
RSPH3
Radial spoke head 3.
   
 
 0.669
MRPS12
Mitochondrial ribosomal protein S12; Belongs to the universal ribosomal protein uS12 family.
   
 
 0.658
DNAAF4
Dynein axonemal assembly factor 4.
   
 0.643
MRPS6
Mitochondrial ribosomal protein S6.
   
   0.640
DYDC2
DPY30 domain containing 2.
   
 0.639
TEKT2
Tektin 2.
   
 
 0.625
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.