STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UQCC2Ubiquinol-cytochrome c reductase complex assembly factor 2. (136 aa)    
Predicted Functional Partners:
UQCC1
Ubiquinol-cytochrome c reductase complex assembly factor 1.
    
 
 0.681
NDUFAF2
NADH:ubiquinone oxidoreductase complex assembly factor 2.
   
  
 0.636
SDHAF4
Succinate dehydrogenase complex assembly factor 4.
   
  
 0.583
NDUFAF1
NADH:ubiquinone oxidoreductase complex assembly factor 1.
   
  
 0.582
COX20
Cytochrome c oxidase assembly factor COX20.
    
 
 0.567
COX7A2
Cytochrome c oxidase subunit 7A2, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembran [...]
   
  
 0.526
COX19
Cytochrome c oxidase assembly factor COX19.
      
 0.510
ENSCAFP00000065700
CHCH domain-containing protein.
      
 0.510
COX17
Cytochrome c oxidase copper chaperone; Copper metallochaperone essential for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. Binds two copper ions and delivers them to the metallochaperone SCO1 which transports the copper ions to the Cu(A) site on the cytochrome c oxidase subunit II (MT-CO2/COX2).
      
 0.483
NAA38
N(alpha)-acetyltransferase 38, NatC auxiliary subunit.
   
    0.483
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.