STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GRM4Glutamate metabotropic receptor 4. (865 aa)    
Predicted Functional Partners:
GRM1
Glutamate metabotropic receptor 1.
  
 
0.915
GRM6
Glutamate metabotropic receptor 6.
  
 
0.902
GRM8
Glutamate metabotropic receptor 8.
  
 
0.902
GRIK4
Glutamate ionotropic receptor kainate type subunit 4.
   
  
 0.797
DLGAP4
DLG associated protein 4.
   
  
 0.681
GRM2
Glutamate metabotropic receptor 2.
  
0.680
GNA12
G protein subunit alpha 12.
   
 0.676
GNA13
G protein subunit alpha 13.
   
 0.675
AGT
Angiotensinogen; Belongs to the serpin family.
   
 
  0.655
CXCL8
Interleukin-8; IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus; Belongs to the intercrine alpha (chemokine CxC) family.
     
  0.650
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.