STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TRIM58Tripartite motif containing 58. (487 aa)    
Predicted Functional Partners:
RO60
Ro60, Y RNA binding protein.
   
 0.923
SQSTM1
Sequestosome 1.
    
 
 0.883
ISG15
ISG15 ubiquitin like modifier.
   
 
 0.826
PLEKHA7
Pleckstrin homology domain containing A7.
    
 
 0.816
USP4
Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.
   
 
 0.788
OR2W3
Olfactory receptor.
      
 0.775
IRF3
Interferon regulatory factor 3.
   
 
 0.770
F6Y518_CANLF
IRF-3 domain-containing protein.
   
 
 0.769
GMPS
Uncharacterized protein.
    
 0.742
UBE2W
UBIQUITIN_CONJUGAT_2 domain-containing protein.
    
 
 0.735
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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