STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AOPEPAminopeptidase O (putative). (798 aa)    
Predicted Functional Partners:
SUN2
Sad1 and UNC84 domain containing 2.
    
 
 0.589
DNM3
Dynamin 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
      
 0.535
ERICH6B
Glutamate rich 6B.
     
 0.501
KRR1
KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.
   
  
 0.498
TOX3
TOX high mobility group box family member 3.
      
 0.490
SUOX
Sulfite oxidase.
      
 0.486
LDLRAD4
Low density lipoprotein receptor class A domain containing 4.
    
 
 0.485
NEIL2
Nei like DNA glycosylase 2.
      
 0.484
DENND1A
DENN domain containing 1A.
      
 0.482
CCDC141
Coiled-coil domain containing 141.
    
 
 0.474
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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