STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKR1B1Uncharacterized protein. (316 aa)    
Predicted Functional Partners:
SORD
Sorbitol dehydrogenase.
  
 0.952
DHDH
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; Belongs to the Gfo/Idh/MocA family.
  
 
 0.745
ALDH3A2
Multidrug and toxin extrusion protein; Belongs to the aldehyde dehydrogenase family.
   
 0.739
HKDC1
Hexokinase domain containing 1.
   
 
 0.738
SPR
Sepiapterin reductase.
   
 0.736
HK2
Hexokinase 2.
   
 
 0.734
HK3
Hexokinase 3.
   
 
 0.733
QDPR
Quinoid dihydropteridine reductase.
   
 0.729
HK1
Hexokinase 1.
   
 
 0.726
RGN
Regucalcin.
  
 
 0.711
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.