STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TPD52L3TPD52 like 3. (122 aa)    
Predicted Functional Partners:
PDIK1L
PDLIM1 interacting kinase 1 like; Belongs to the protein kinase superfamily.
   
  
 0.566
IFT74
Intraflagellar transport 74.
    
 
 0.534
MTMR2
Myotubularin related protein 2.
   
  
 0.515
PAFAH1B2
Platelet activating factor acetylhydrolase 1b catalytic subunit 2.
    
 
 0.515
MEMO1
Mediator of cell motility 1.
      
 0.507
GLRA1
Glycine receptor alpha 1; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
   
  
 0.491
ITIH2
Inter-alpha-trypsin inhibitor heavy chain 2.
   
  
 0.453
MAPK7
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
    
 
 0.427
SCN8A
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
      
 0.407
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.