STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SLC26A8Testis anion transporter 1. (965 aa)    
Predicted Functional Partners:
PRIM2
DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands.
      
 0.791
MOCS1
Molybdenum cofactor synthesis 1.
     
 0.632
SRPK1
SRSF protein kinase 1.
 
  
 
 0.619
LHFPL5
LHFPL tetraspan subfamily member 5.
   
  
 0.606
TMEM262
Transmembrane protein 262.
      
 0.591
MTHFR
Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
   
  
 0.552
EFCAB9
EF-hand calcium binding domain 9.
   
 
 0.539
DEFB119
Beta-defensin 119; Has antibacterial activity; Belongs to the beta-defensin family.
      
 0.539
PLA2G4A
Phospholipase A2.
     
 0.505
STK38
Non-specific serine/threonine protein kinase.
      
 0.482
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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