STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PNPLA1PNPLA domain-containing protein. (565 aa)    
Predicted Functional Partners:
ABHD5
Abhydrolase domain containing 5.
    
 
 0.928
NIPAL4
NIPA like domain containing 4.
      
 0.894
CYP4F22
Cytochrome P450 family 4 subfamily F member 22; Belongs to the cytochrome P450 family.
      
 0.889
CERS3
Ceramide synthase 3.
   
  
 0.878
TGM1
Protein-glutamine gamma-glutamyltransferase K; Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Responsible for cross-linking epidermal proteins during formation of the stratum corneum. Involved in cell proliferation (By similarity); Belongs to the transglutaminase superfamily. Transglutaminase family.
   
  
 0.875
SLC27A4
Solute carrier family 27 member 4.
    
 
 0.865
ABCA12
ATP binding cassette subfamily A member 12.
   
  
 0.848
SDR9C7
Short chain dehydrogenase/reductase family 9C member 7; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
  
 0.807
ASPRV1
Aspartic peptidase retroviral like 1.
   
  
 0.807
KRT10
Keratin, type I cytoskeletal 10; Plays a role in the establishment of the epidermal barrier on plantar skin; Belongs to the intermediate filament family.
   
  
 0.715
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.