STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DDX17DEAD-box helicase 17; Belongs to the DEAD box helicase family. (729 aa)    
Predicted Functional Partners:
DHX9
DExH-box helicase 9.
   
 
 0.795
DHX15
DEAH-box helicase 15.
   
 
 0.782
MRPL16
Ribosomal_L16 domain-containing protein; Belongs to the universal ribosomal protein uL16 family.
   
 
 0.754
DDX5
Uncharacterized protein; Belongs to the DEAD box helicase family.
  
 
0.747
HNRNPM
Heterogeneous nuclear ribonucleoprotein M.
   
 
 0.739
GNL2
Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.
   
 
 0.733
ENSCAFP00000053603
Uncharacterized protein.
   
 
 0.729
ANP32A
Acidic leucine-rich nuclear phosphoprotein 32 family member A; Implicated in a number of cellular processes, including proliferation, differentiation, caspase-dependent and caspase- independent apoptosis, suppression of transformation (tumor suppressor), inhibition of protein phosphatase 2A, regulation of mRNA trafficking and stability in association with ELAVL1, and inhibition of acetyltransferases as part of the INHAT (inhibitor of histone acetyltransferases) complex. Plays a role in E4F1-mediated transcriptional repression (By similarity).
   
 
 0.716
DGCR8
DGCR8 microprocessor complex subunit.
    
 
 0.711
DKC1
Dyskerin pseudouridine synthase 1.
  
 
 0.705
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.