Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
STK38Non-specific serine/threonine protein kinase. (586 aa)    
Predicted Functional Partners:
LOC484191
Uncharacterized protein.
 
  
   0.913
SMG1
SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family.
    
 
 0.905
MOB1A
MOB kinase activator 1A.
    
 0.849
ENSCAFP00000054742
DUF1908 domain-containing protein.
 
  
  0.847
MOB2
MOB kinase activator 2.
   
 0.782
MOB1B
MOB kinase activator 1B.
    
 0.687
CDC14B
Cell division cycle 14B.
   
 0.668
CDC14A
Cell division cycle 14A.
   
 0.668
S100B
Protein S100; Belongs to the S-100 family.
    
   0.627
FRYL
FRY like transcription coactivator.
   
 
 0.624
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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