Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SLC16A8Solute carrier family 16 member 8. (507 aa)    
Predicted Functional Partners:
RDH5
Retinol dehydrogenase 5; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
      
 0.692
SLC39A12
Solute carrier family 39 member 12.
      
 0.673
BSG
Basigin.
   
 
 0.644
SLC45A1
Solute carrier family 45 member 1.
      
 0.596
SLC4A5
Anion exchange protein.
      
 0.577
LOC483364
Tetraspanin.
      
 0.571
B3GLCT
Beta 3-glucosyltransferase.
      
 0.565
RAD51B
RAD51 paralog B.
      
 0.539
SLC6A15
Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
      
 0.528
FILIP1L
Filamin A interacting protein 1 like.
    
 
 0.503
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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