STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PICK1Protein interacting with PRKCA 1. (417 aa)    
Predicted Functional Partners:
GRIA2
Glutamate ionotropic receptor AMPA type subunit 2.
    
 
 0.976
TPT1
Tumor protein, translationally-controlled 1; Belongs to the TCTP family.
    
   0.926
NHSL2
NHS like 2.
    
   0.926
GRIA3
Glutamate ionotropic receptor AMPA type subunit 3.
    
 
 0.901
GRIA1
Glutamate ionotropic receptor AMPA type subunit 1.
    
 
 0.891
GRIA4
Glutamate ionotropic receptor AMPA type subunit 4.
    
 
 0.854
GRIP2
Glutamate receptor interacting protein 2.
   
 
 0.831
DPY19L2
Dpy-19 like 2.
      
 0.828
SPATA16
Spermatogenesis associated 16.
      
 0.808
ATP6AP1
ATPase H+ transporting accessory protein 1.
    
 
 0.777
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.