STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GALR3Galanin receptor 3; Belongs to the G-protein coupled receptor 1 family. (370 aa)    
Predicted Functional Partners:
GAL
Galanin message-associated peptide; Endocrine hormone of the central and peripheral nervous systems that binds and activates the G protein-coupled receptors GALR1, GALR2, and GALR3. This small neuropeptide may regulate diverse physiologic functions including contraction of smooth muscle of the gastrointestinal and genitourinary tract, growth hormone and insulin release and adrenal secretion; Belongs to the galanin family.
    
 0.995
GALR1
Galanin receptor 1; Belongs to the G-protein coupled receptor 1 family.
   
 
0.927
GALR2
Galanin receptor 2; Belongs to the G-protein coupled receptor 1 family.
  
 
0.907
SPX
Spexin hormone.
   
 
 0.729
POMC
Proopiomelanocortin.
   
 0.597
PMCH
Neuropeptide-glutamic acid-isoleucine; MCH may act as a neurotransmitter or neuromodulator in a broad array of neuronal functions directed toward the regulation of goal-directed behavior, such as food intake, and general arousal.
     
 0.577
MCHR1
Melanin concentrating hormone receptor 1.
   
 
0.575
CCDC117
Coiled-coil domain containing 117.
      
 0.563
ADGRL4
Adhesion G protein-coupled receptor L4; Belongs to the G-protein coupled receptor 2 family.
      
 0.563
MOSPD1
Motile sperm domain containing 1.
      
 0.561
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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