GALR3 protein (Canis lupus familiaris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

GALR3

Galanin receptor 3; Belongs to the G-protein coupled receptor 1 family. (370 aa)

Predicted Functional Partners:

GAL

0.988

SPX

0.942

GALP

0.893

GALR1

0.872

GALR2

0.813

UTS2R

0.684

POMC

0.671

GNAT3

0.640

GNAI3

0.640

GNAI2

0.640

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GAL	GALP	ENSCAFP00000015855	ENSCAFP00000036884	Galanin message-associated peptide; Endocrine hormone of the central and peripheral nervous systems that binds and activates the G protein-coupled receptors GALR1, GALR2, and GALR3. This small neuropeptide may regulate diverse physiologic functions including contraction of smooth muscle of the gastrointestinal and genitourinary tract, growth hormone and insulin release and adrenal secretion; Belongs to the galanin family.	Galanin like peptide.	0.977
GAL	GALR1	ENSCAFP00000015855	ENSCAFP00000000020	Galanin message-associated peptide; Endocrine hormone of the central and peripheral nervous systems that binds and activates the G protein-coupled receptors GALR1, GALR2, and GALR3. This small neuropeptide may regulate diverse physiologic functions including contraction of smooth muscle of the gastrointestinal and genitourinary tract, growth hormone and insulin release and adrenal secretion; Belongs to the galanin family.	Galanin receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.999
GAL	GALR2	ENSCAFP00000015855	ENSCAFP00000007485	Galanin message-associated peptide; Endocrine hormone of the central and peripheral nervous systems that binds and activates the G protein-coupled receptors GALR1, GALR2, and GALR3. This small neuropeptide may regulate diverse physiologic functions including contraction of smooth muscle of the gastrointestinal and genitourinary tract, growth hormone and insulin release and adrenal secretion; Belongs to the galanin family.	Galanin receptor 2; Belongs to the G-protein coupled receptor 1 family.	0.990
GAL	GALR3	ENSCAFP00000015855	ENSCAFP00000002089	Galanin message-associated peptide; Endocrine hormone of the central and peripheral nervous systems that binds and activates the G protein-coupled receptors GALR1, GALR2, and GALR3. This small neuropeptide may regulate diverse physiologic functions including contraction of smooth muscle of the gastrointestinal and genitourinary tract, growth hormone and insulin release and adrenal secretion; Belongs to the galanin family.	Galanin receptor 3; Belongs to the G-protein coupled receptor 1 family.	0.988
GAL	POMC	ENSCAFP00000015855	ENSCAFP00000006163	Galanin message-associated peptide; Endocrine hormone of the central and peripheral nervous systems that binds and activates the G protein-coupled receptors GALR1, GALR2, and GALR3. This small neuropeptide may regulate diverse physiologic functions including contraction of smooth muscle of the gastrointestinal and genitourinary tract, growth hormone and insulin release and adrenal secretion; Belongs to the galanin family.	Proopiomelanocortin.	0.472
GAL	SPX	ENSCAFP00000015855	ENSCAFP00000018049	Galanin message-associated peptide; Endocrine hormone of the central and peripheral nervous systems that binds and activates the G protein-coupled receptors GALR1, GALR2, and GALR3. This small neuropeptide may regulate diverse physiologic functions including contraction of smooth muscle of the gastrointestinal and genitourinary tract, growth hormone and insulin release and adrenal secretion; Belongs to the galanin family.	Spexin hormone.	0.518
GALP	GAL	ENSCAFP00000036884	ENSCAFP00000015855	Galanin like peptide.	Galanin message-associated peptide; Endocrine hormone of the central and peripheral nervous systems that binds and activates the G protein-coupled receptors GALR1, GALR2, and GALR3. This small neuropeptide may regulate diverse physiologic functions including contraction of smooth muscle of the gastrointestinal and genitourinary tract, growth hormone and insulin release and adrenal secretion; Belongs to the galanin family.	0.977
GALP	GALR1	ENSCAFP00000036884	ENSCAFP00000000020	Galanin like peptide.	Galanin receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.933
GALP	GALR2	ENSCAFP00000036884	ENSCAFP00000007485	Galanin like peptide.	Galanin receptor 2; Belongs to the G-protein coupled receptor 1 family.	0.891
GALP	GALR3	ENSCAFP00000036884	ENSCAFP00000002089	Galanin like peptide.	Galanin receptor 3; Belongs to the G-protein coupled receptor 1 family.	0.893
GALP	SPX	ENSCAFP00000036884	ENSCAFP00000018049	Galanin like peptide.	Spexin hormone.	0.458
GALR1	GAL	ENSCAFP00000000020	ENSCAFP00000015855	Galanin receptor 1; Belongs to the G-protein coupled receptor 1 family.	Galanin message-associated peptide; Endocrine hormone of the central and peripheral nervous systems that binds and activates the G protein-coupled receptors GALR1, GALR2, and GALR3. This small neuropeptide may regulate diverse physiologic functions including contraction of smooth muscle of the gastrointestinal and genitourinary tract, growth hormone and insulin release and adrenal secretion; Belongs to the galanin family.	0.999
GALR1	GALP	ENSCAFP00000000020	ENSCAFP00000036884	Galanin receptor 1; Belongs to the G-protein coupled receptor 1 family.	Galanin like peptide.	0.933
GALR1	GALR2	ENSCAFP00000000020	ENSCAFP00000007485	Galanin receptor 1; Belongs to the G-protein coupled receptor 1 family.	Galanin receptor 2; Belongs to the G-protein coupled receptor 1 family.	0.876
GALR1	GALR3	ENSCAFP00000000020	ENSCAFP00000002089	Galanin receptor 1; Belongs to the G-protein coupled receptor 1 family.	Galanin receptor 3; Belongs to the G-protein coupled receptor 1 family.	0.872
GALR1	GNAI2	ENSCAFP00000000020	ENSCAFP00000033576	Galanin receptor 1; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein G(i) subunit alpha-2; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta- adrenergic stimuli. May play a role in cell division (By similarity).	0.698
GALR1	GNAI3	ENSCAFP00000000020	ENSCAFP00000029356	Galanin receptor 1; Belongs to the G-protein coupled receptor 1 family.	G protein subunit alpha i3.	0.698
GALR1	GNAT3	ENSCAFP00000000020	ENSCAFP00000020146	Galanin receptor 1; Belongs to the G-protein coupled receptor 1 family.	G protein subunit alpha transducin 3.	0.623
GALR1	POMC	ENSCAFP00000000020	ENSCAFP00000006163	Galanin receptor 1; Belongs to the G-protein coupled receptor 1 family.	Proopiomelanocortin.	0.645
GALR1	SPX	ENSCAFP00000000020	ENSCAFP00000018049	Galanin receptor 1; Belongs to the G-protein coupled receptor 1 family.	Spexin hormone.	0.949