MEST protein (Canis lupus familiaris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

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Co-occurrence

Co-expression

Experiments

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[Homology]

Score

MEST

Mesoderm specific transcript. (340 aa)

Predicted Functional Partners:

NNAT

0.774

PLAGL1

0.735

COPG2

0.668

SGCE

0.660

SNRPN

0.651

PEG10

0.650

IGF2R

0.648

GRB10

0.631

SNU13

0.603

ZNF597

0.599

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
COPG2	GRB10	ENSCAFP00000002070	ENSCAFP00000005101	Coatomer protein complex subunit gamma 2.	Growth factor receptor bound protein 10.	0.401
COPG2	IGF2R	ENSCAFP00000002070	ENSCAFP00000036713	Coatomer protein complex subunit gamma 2.	Cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor protein.	0.429
COPG2	MEST	ENSCAFP00000002070	ENSCAFP00000002104	Coatomer protein complex subunit gamma 2.	Mesoderm specific transcript.	0.668
COPG2	PEG10	ENSCAFP00000002070	ENSCAFP00000041426	Coatomer protein complex subunit gamma 2.	CCHC-type domain-containing protein.	0.462
COPG2	PLAGL1	ENSCAFP00000002070	ENSCAFP00000063900	Coatomer protein complex subunit gamma 2.	PLAG1 like zinc finger 1.	0.442
COPG2	SGCE	ENSCAFP00000002070	ENSCAFP00000049660	Coatomer protein complex subunit gamma 2.	Sarcoglycan epsilon.	0.458
COPG2	SNRPN	ENSCAFP00000002070	ENSCAFP00000014878	Coatomer protein complex subunit gamma 2.	Small nuclear ribonucleoprotein-associated protein.	0.592
GRB10	COPG2	ENSCAFP00000005101	ENSCAFP00000002070	Growth factor receptor bound protein 10.	Coatomer protein complex subunit gamma 2.	0.401
GRB10	IGF2R	ENSCAFP00000005101	ENSCAFP00000036713	Growth factor receptor bound protein 10.	Cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor protein.	0.623
GRB10	MEST	ENSCAFP00000005101	ENSCAFP00000002104	Growth factor receptor bound protein 10.	Mesoderm specific transcript.	0.631
GRB10	NNAT	ENSCAFP00000005101	ENSCAFP00000012912	Growth factor receptor bound protein 10.	Neuronatin.	0.529
GRB10	PEG10	ENSCAFP00000005101	ENSCAFP00000041426	Growth factor receptor bound protein 10.	CCHC-type domain-containing protein.	0.532
GRB10	PLAGL1	ENSCAFP00000005101	ENSCAFP00000063900	Growth factor receptor bound protein 10.	PLAG1 like zinc finger 1.	0.598
GRB10	SGCE	ENSCAFP00000005101	ENSCAFP00000049660	Growth factor receptor bound protein 10.	Sarcoglycan epsilon.	0.457
GRB10	SNRPN	ENSCAFP00000005101	ENSCAFP00000014878	Growth factor receptor bound protein 10.	Small nuclear ribonucleoprotein-associated protein.	0.623
IGF2R	COPG2	ENSCAFP00000036713	ENSCAFP00000002070	Cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor protein.	Coatomer protein complex subunit gamma 2.	0.429
IGF2R	GRB10	ENSCAFP00000036713	ENSCAFP00000005101	Cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor protein.	Growth factor receptor bound protein 10.	0.623
IGF2R	MEST	ENSCAFP00000036713	ENSCAFP00000002104	Cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor protein.	Mesoderm specific transcript.	0.648
IGF2R	NNAT	ENSCAFP00000036713	ENSCAFP00000012912	Cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor protein.	Neuronatin.	0.576
IGF2R	PEG10	ENSCAFP00000036713	ENSCAFP00000041426	Cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor protein.	CCHC-type domain-containing protein.	0.599