CPA4 protein (Canis lupus familiaris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

CPA4

Carboxypeptidase A4. (421 aa)

Predicted Functional Partners:

CPA3

0.915

LOC478196

0.904

CPA1

0.881

LOC478220

0.880

SCGB1C1

0.877

PPY

0.758

KBTBD3

0.618

COPG2

0.606

KLF14

0.603

KLHL8

0.597

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
COPG2	CPA4	ENSCAFP00000002070	ENSCAFP00000002144	Coatomer protein complex subunit gamma 2.	Carboxypeptidase A4.	0.606
COPG2	KBTBD3	ENSCAFP00000002070	ENSCAFP00000021797	Coatomer protein complex subunit gamma 2.	Kelch repeat and BTB domain containing 3.	0.482
COPG2	KLF14	ENSCAFP00000002070	ENSCAFP00000033964	Coatomer protein complex subunit gamma 2.	Kruppel like factor 14.	0.454
CPA1	CPA3	ENSCAFP00000065526	ENSCAFP00000058575	Carboxypeptidase A1.	Carboxypeptidase B.	0.925
CPA1	CPA4	ENSCAFP00000065526	ENSCAFP00000002144	Carboxypeptidase A1.	Carboxypeptidase A4.	0.881
CPA1	LOC478196	ENSCAFP00000065526	ENSCAFP00000046922	Carboxypeptidase A1.	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	0.954
CPA1	LOC478220	ENSCAFP00000065526	ENSCAFP00000044535	Carboxypeptidase A1.	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	0.961
CPA1	PPY	ENSCAFP00000065526	ENSCAFP00000021236	Carboxypeptidase A1.	Pancreatic icosapeptide; Pancreatic hormone is synthesized in pancreatic islets of Langerhans and acts as a regulator of pancreatic and gastrointestinal functions.	0.851
CPA1	SCGB1C1	ENSCAFP00000065526	ENSCAFP00000009606	Carboxypeptidase A1.	Uncharacterized protein.	0.719
CPA3	CPA1	ENSCAFP00000058575	ENSCAFP00000065526	Carboxypeptidase B.	Carboxypeptidase A1.	0.925
CPA3	CPA4	ENSCAFP00000058575	ENSCAFP00000002144	Carboxypeptidase B.	Carboxypeptidase A4.	0.915
CPA4	COPG2	ENSCAFP00000002144	ENSCAFP00000002070	Carboxypeptidase A4.	Coatomer protein complex subunit gamma 2.	0.606
CPA4	CPA1	ENSCAFP00000002144	ENSCAFP00000065526	Carboxypeptidase A4.	Carboxypeptidase A1.	0.881
CPA4	CPA3	ENSCAFP00000002144	ENSCAFP00000058575	Carboxypeptidase A4.	Carboxypeptidase B.	0.915
CPA4	KBTBD3	ENSCAFP00000002144	ENSCAFP00000021797	Carboxypeptidase A4.	Kelch repeat and BTB domain containing 3.	0.618
CPA4	KLF14	ENSCAFP00000002144	ENSCAFP00000033964	Carboxypeptidase A4.	Kruppel like factor 14.	0.603
CPA4	KLHL8	ENSCAFP00000002144	ENSCAFP00000013957	Carboxypeptidase A4.	Kelch like family member 8.	0.597
CPA4	LOC478196	ENSCAFP00000002144	ENSCAFP00000046922	Carboxypeptidase A4.	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	0.904
CPA4	LOC478220	ENSCAFP00000002144	ENSCAFP00000044535	Carboxypeptidase A4.	Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.	0.880
CPA4	PPY	ENSCAFP00000002144	ENSCAFP00000021236	Carboxypeptidase A4.	Pancreatic icosapeptide; Pancreatic hormone is synthesized in pancreatic islets of Langerhans and acts as a regulator of pancreatic and gastrointestinal functions.	0.758