STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SSMEM1Serine rich single-pass membrane protein 1. (244 aa)    
Predicted Functional Partners:
SPACA1
Sperm acrosome associated 1.
      
 0.923
TSSK4
Testis specific serine kinase 4.
   
  
 0.785
LRGUK
Leucine rich repeats and guanylate kinase domain containing.
   
  
 0.782
KSR2
Kinase suppressor of ras 2.
      
 0.770
CIB4
Calcium and integrin binding family member 4.
      
 0.769
SPATA46
Spermatogenesis associated 46.
      
 0.726
VPS54
VPS54 subunit of GARP complex.
      
 0.703
SPEF2
Sperm flagellar 2.
   
  
 0.700
KLC3
Kinesin light chain 3.
      
 0.691
TMED4
Transmembrane p24 trafficking protein 4.
      
 0.687
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.