STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NCF4Neutrophil cytosolic factor 4. (339 aa)    
Predicted Functional Partners:
CYBA
Cytochrome b-245 alpha chain.
   
 0.999
NCF2
Neutrophil cytosolic factor 2.
   
 0.999
NOX1
NADPH oxidase 1.
   
 0.994
NOX3
Predicted NADPH oxidase-3.
   
 0.984
NOXA1
NADPH oxidase activator 1.
   
 0.975
NOX5
NADPH oxidase 5.
   
 0.971
RAC2
Rac family small GTPase 2.
   
 0.965
DUOX2
Dual oxidase 2.
   
 0.957
DUOX1
Dual oxidase 1; Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain.
   
 0.957
CYBB
Cytochrome b-245 beta chain.
   
 0.954
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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