STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TSPAN33Tetraspanin. (425 aa)    
Predicted Functional Partners:
PIWIL4
Piwi like RNA-mediated gene silencing 4; Belongs to the argonaute family.
      
 0.794
ADAM10
ADAM metallopeptidase domain 10.
    
 0.699
PLEKHA7
Pleckstrin homology domain containing A7.
    
 0.682
TM6SF1
Transmembrane 6 superfamily member 1.
      
 0.674
PTCH1
Patched 1.
    
  0.617
EVC2
EvC ciliary complex subunit 2.
     
  0.605
EVC
EvC ciliary complex subunit 1.
     
  0.605
MOSMO
Modulator of smoothened.
     
  0.605
CSNK1A1
Casein kinase 1 alpha 1; Belongs to the protein kinase superfamily.
     
  0.605
MGRN1
Mahogunin ring finger 1.
     
  0.605
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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