SHARPIN protein (Canis lupus familiaris) - STRING interaction network

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Score

SHARPIN

SHANK associated RH domain interactor. (860 aa)

Predicted Functional Partners:

RBCK1

0.999

IRF9

0.999

OTULIN

0.990

IKBKG

0.972

TNFRSF1A

0.972

RIPK1

0.971

TNF

0.970

XIAP

0.965

TRAF2

0.960

BIRC2

0.952

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BIRC2	IKBKG	ENSCAFP00000022277	ENSCAFP00000028998	Baculoviral IAP repeat containing 2.	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	0.890
BIRC2	IRF9	ENSCAFP00000022277	ENSCAFP00000017662	Baculoviral IAP repeat containing 2.	Uncharacterized protein.	0.969
BIRC2	RBCK1	ENSCAFP00000022277	ENSCAFP00000010292	Baculoviral IAP repeat containing 2.	RANBP2-type and C3HC4-type zinc finger containing 1.	0.938
BIRC2	RIPK1	ENSCAFP00000022277	ENSCAFP00000013721	Baculoviral IAP repeat containing 2.	Receptor interacting serine/threonine kinase 1.	0.974
BIRC2	SHARPIN	ENSCAFP00000022277	ENSCAFP00000002217	Baculoviral IAP repeat containing 2.	SHANK associated RH domain interactor.	0.952
BIRC2	TNF	ENSCAFP00000022277	ENSCAFP00000000739	Baculoviral IAP repeat containing 2.	Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...]	0.897
BIRC2	TNFRSF1A	ENSCAFP00000022277	ENSCAFP00000062480	Baculoviral IAP repeat containing 2.	TNF receptor superfamily member 1A.	0.974
BIRC2	TRAF2	ENSCAFP00000022277	ENSCAFP00000028895	Baculoviral IAP repeat containing 2.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.973
BIRC2	XIAP	ENSCAFP00000022277	ENSCAFP00000034255	Baculoviral IAP repeat containing 2.	Baculoviral IAP-repeat containing protein 4.	0.966
IKBKG	BIRC2	ENSCAFP00000028998	ENSCAFP00000022277	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	Baculoviral IAP repeat containing 2.	0.890
IKBKG	IRF9	ENSCAFP00000028998	ENSCAFP00000017662	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	Uncharacterized protein.	0.975
IKBKG	RBCK1	ENSCAFP00000028998	ENSCAFP00000010292	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	RANBP2-type and C3HC4-type zinc finger containing 1.	0.974
IKBKG	RIPK1	ENSCAFP00000028998	ENSCAFP00000013721	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	Receptor interacting serine/threonine kinase 1.	0.995
IKBKG	SHARPIN	ENSCAFP00000028998	ENSCAFP00000002217	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	SHANK associated RH domain interactor.	0.972
IKBKG	TNF	ENSCAFP00000028998	ENSCAFP00000000739	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...]	0.981
IKBKG	TNFRSF1A	ENSCAFP00000028998	ENSCAFP00000062480	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	TNF receptor superfamily member 1A.	0.980
IKBKG	TRAF2	ENSCAFP00000028998	ENSCAFP00000028895	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.982
IKBKG	XIAP	ENSCAFP00000028998	ENSCAFP00000034255	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	Baculoviral IAP-repeat containing protein 4.	0.764
IRF9	BIRC2	ENSCAFP00000017662	ENSCAFP00000022277	Uncharacterized protein.	Baculoviral IAP repeat containing 2.	0.969
IRF9	IKBKG	ENSCAFP00000017662	ENSCAFP00000028998	Uncharacterized protein.	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.	0.975