STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MROH1Maestro heat like repeat family member 1. (1486 aa)    
Predicted Functional Partners:
KANSL2
KAT8 regulatory NSL complex subunit 2.
      
 0.763
MATR3
Uncharacterized protein.
      
 0.599
BCCIP
BRCA2 and CDKN1A-interacting protein; May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ); Belongs to the BCP1 family.
      
 0.591
PTBP1
Polypyrimidine tract binding protein 1.
      
 0.534
CPSF1
Cleavage and polyadenylation specific factor 1.
   
  
 0.509
CYHR1
Cysteine and histidine rich 1.
   
  
 0.478
KHDRBS1
KH RNA binding domain containing, signal transduction associated 1.
      
 0.465
CSTF2
Cleavage stimulation factor subunit 2.
      
 0.427
SAFB2
Scaffold attachment factor B2.
      
 0.425
CELF2
CUGBP Elav-like family member 2.
      
 0.425
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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