STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MROH1Maestro heat like repeat family member 1. (1486 aa)    
Predicted Functional Partners:
KANSL2
KAT8 regulatory NSL complex subunit 2.
      
 0.844
CPSF1
Cleavage and polyadenylation specific factor 1.
   
  
 0.743
CYHR1
Cysteine and histidine rich 1.
   
  
 0.678
ARHGAP39
Rho GTPase activating protein 39.
      
 0.636
TLCD4
TLCD4-RWDD3 readthrough.
   
  
 0.609
NRIP2
Nuclear receptor interacting protein 2.
      
 0.605
MAPK15
Mitogen-activated protein kinase.
      
 0.599
MATR3
Uncharacterized protein.
      
 0.591
PTBP1
Polypyrimidine tract binding protein 1.
      
 0.573
BCCIP
BRCA2 and CDKN1A-interacting protein; May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ); Belongs to the BCP1 family.
      
 0.556
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.