TXN2 protein (Canis lupus familiaris) - STRING interaction network

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Score

TXN2

Thioredoxin 2. (163 aa)

Predicted Functional Partners:

TXNIP

0.975

MAP3K5

0.968

TXNRD2

0.922

DAXX

0.891

PRDX3

0.869

MAP3K6

0.866

LOC474798

0.861

J9NWJ5_CANLF

0.851

ENSCAFP00000056985

0.831

TXNDC2

0.815

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DAXX	ENSCAFP00000056985	ENSCAFP00000048726	ENSCAFP00000056985	Death domain-associated protein 6; Transcription corepressor known to repress transcriptional potential of several sumoylated transcription factors. Down-regulates basal and activated transcription. Its transcription repressor activity is modulated by recruiting it to subnuclear compartments like the nucleolus or PML/POD/ND10 nuclear bodies through interactions with MCSR1 and PML, respectively. Seems to regulate transcription in PML/POD/ND10 nuclear bodies together with PML and may influence TNFRSF6-dependent apoptosis thereby. Inhibits transcriptional activation of PAX3 and ETS1 throu [...]	Thioredoxin domain-containing protein.	0.653
DAXX	J9NWJ5_CANLF	ENSCAFP00000048726	ENSCAFP00000037540	Death domain-associated protein 6; Transcription corepressor known to repress transcriptional potential of several sumoylated transcription factors. Down-regulates basal and activated transcription. Its transcription repressor activity is modulated by recruiting it to subnuclear compartments like the nucleolus or PML/POD/ND10 nuclear bodies through interactions with MCSR1 and PML, respectively. Seems to regulate transcription in PML/POD/ND10 nuclear bodies together with PML and may influence TNFRSF6-dependent apoptosis thereby. Inhibits transcriptional activation of PAX3 and ETS1 throu [...]	Thioredoxin; Belongs to the thioredoxin family.	0.653
DAXX	LOC474798	ENSCAFP00000048726	ENSCAFP00000045366	Death domain-associated protein 6; Transcription corepressor known to repress transcriptional potential of several sumoylated transcription factors. Down-regulates basal and activated transcription. Its transcription repressor activity is modulated by recruiting it to subnuclear compartments like the nucleolus or PML/POD/ND10 nuclear bodies through interactions with MCSR1 and PML, respectively. Seems to regulate transcription in PML/POD/ND10 nuclear bodies together with PML and may influence TNFRSF6-dependent apoptosis thereby. Inhibits transcriptional activation of PAX3 and ETS1 throu [...]	Thioredoxin domain-containing protein.	0.653
DAXX	MAP3K5	ENSCAFP00000048726	ENSCAFP00000000362	Death domain-associated protein 6; Transcription corepressor known to repress transcriptional potential of several sumoylated transcription factors. Down-regulates basal and activated transcription. Its transcription repressor activity is modulated by recruiting it to subnuclear compartments like the nucleolus or PML/POD/ND10 nuclear bodies through interactions with MCSR1 and PML, respectively. Seems to regulate transcription in PML/POD/ND10 nuclear bodies together with PML and may influence TNFRSF6-dependent apoptosis thereby. Inhibits transcriptional activation of PAX3 and ETS1 throu [...]	Mitogen-activated protein kinase kinase kinase 5.	0.995
DAXX	MAP3K6	ENSCAFP00000048726	ENSCAFP00000017922	Death domain-associated protein 6; Transcription corepressor known to repress transcriptional potential of several sumoylated transcription factors. Down-regulates basal and activated transcription. Its transcription repressor activity is modulated by recruiting it to subnuclear compartments like the nucleolus or PML/POD/ND10 nuclear bodies through interactions with MCSR1 and PML, respectively. Seems to regulate transcription in PML/POD/ND10 nuclear bodies together with PML and may influence TNFRSF6-dependent apoptosis thereby. Inhibits transcriptional activation of PAX3 and ETS1 throu [...]	Mitogen-activated protein kinase kinase kinase 6.	0.932
DAXX	TXN2	ENSCAFP00000048726	ENSCAFP00000002247	Death domain-associated protein 6; Transcription corepressor known to repress transcriptional potential of several sumoylated transcription factors. Down-regulates basal and activated transcription. Its transcription repressor activity is modulated by recruiting it to subnuclear compartments like the nucleolus or PML/POD/ND10 nuclear bodies through interactions with MCSR1 and PML, respectively. Seems to regulate transcription in PML/POD/ND10 nuclear bodies together with PML and may influence TNFRSF6-dependent apoptosis thereby. Inhibits transcriptional activation of PAX3 and ETS1 throu [...]	Thioredoxin 2.	0.891
DAXX	TXNDC2	ENSCAFP00000048726	ENSCAFP00000027629	Death domain-associated protein 6; Transcription corepressor known to repress transcriptional potential of several sumoylated transcription factors. Down-regulates basal and activated transcription. Its transcription repressor activity is modulated by recruiting it to subnuclear compartments like the nucleolus or PML/POD/ND10 nuclear bodies through interactions with MCSR1 and PML, respectively. Seems to regulate transcription in PML/POD/ND10 nuclear bodies together with PML and may influence TNFRSF6-dependent apoptosis thereby. Inhibits transcriptional activation of PAX3 and ETS1 throu [...]	Thioredoxin domain containing 2.	0.619
ENSCAFP00000056985	DAXX	ENSCAFP00000056985	ENSCAFP00000048726	Thioredoxin domain-containing protein.	Death domain-associated protein 6; Transcription corepressor known to repress transcriptional potential of several sumoylated transcription factors. Down-regulates basal and activated transcription. Its transcription repressor activity is modulated by recruiting it to subnuclear compartments like the nucleolus or PML/POD/ND10 nuclear bodies through interactions with MCSR1 and PML, respectively. Seems to regulate transcription in PML/POD/ND10 nuclear bodies together with PML and may influence TNFRSF6-dependent apoptosis thereby. Inhibits transcriptional activation of PAX3 and ETS1 throu [...]	0.653
ENSCAFP00000056985	MAP3K5	ENSCAFP00000056985	ENSCAFP00000000362	Thioredoxin domain-containing protein.	Mitogen-activated protein kinase kinase kinase 5.	0.883
ENSCAFP00000056985	MAP3K6	ENSCAFP00000056985	ENSCAFP00000017922	Thioredoxin domain-containing protein.	Mitogen-activated protein kinase kinase kinase 6.	0.738
ENSCAFP00000056985	PRDX3	ENSCAFP00000056985	ENSCAFP00000017833	Thioredoxin domain-containing protein.	Thioredoxin domain-containing protein.	0.603
ENSCAFP00000056985	TXN2	ENSCAFP00000056985	ENSCAFP00000002247	Thioredoxin domain-containing protein.	Thioredoxin 2.	0.831
ENSCAFP00000056985	TXNIP	ENSCAFP00000056985	ENSCAFP00000016786	Thioredoxin domain-containing protein.	Thioredoxin interacting protein.	0.882
ENSCAFP00000056985	TXNRD2	ENSCAFP00000056985	ENSCAFP00000021267	Thioredoxin domain-containing protein.	Thioredoxin reductase 2.	0.590
J9NWJ5_CANLF	DAXX	ENSCAFP00000037540	ENSCAFP00000048726	Thioredoxin; Belongs to the thioredoxin family.	Death domain-associated protein 6; Transcription corepressor known to repress transcriptional potential of several sumoylated transcription factors. Down-regulates basal and activated transcription. Its transcription repressor activity is modulated by recruiting it to subnuclear compartments like the nucleolus or PML/POD/ND10 nuclear bodies through interactions with MCSR1 and PML, respectively. Seems to regulate transcription in PML/POD/ND10 nuclear bodies together with PML and may influence TNFRSF6-dependent apoptosis thereby. Inhibits transcriptional activation of PAX3 and ETS1 throu [...]	0.653
J9NWJ5_CANLF	MAP3K5	ENSCAFP00000037540	ENSCAFP00000000362	Thioredoxin; Belongs to the thioredoxin family.	Mitogen-activated protein kinase kinase kinase 5.	0.883
J9NWJ5_CANLF	MAP3K6	ENSCAFP00000037540	ENSCAFP00000017922	Thioredoxin; Belongs to the thioredoxin family.	Mitogen-activated protein kinase kinase kinase 6.	0.738
J9NWJ5_CANLF	PRDX3	ENSCAFP00000037540	ENSCAFP00000017833	Thioredoxin; Belongs to the thioredoxin family.	Thioredoxin domain-containing protein.	0.740
J9NWJ5_CANLF	TXN2	ENSCAFP00000037540	ENSCAFP00000002247	Thioredoxin; Belongs to the thioredoxin family.	Thioredoxin 2.	0.851
J9NWJ5_CANLF	TXNIP	ENSCAFP00000037540	ENSCAFP00000016786	Thioredoxin; Belongs to the thioredoxin family.	Thioredoxin interacting protein.	0.952