STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KIF6Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (764 aa)    
Predicted Functional Partners:
RAI14
Retinoic acid induced 14.
    
 
 0.842
PDE11A
Phosphodiesterase.
   
  
 0.696
KIFAP3
Kinesin associated protein 3.
   
 
 0.627
LOC483842
Uncharacterized protein.
   
  
 0.607
PDE10A
Phosphodiesterase.
   
  
 0.606
RPAIN
RPA interacting protein.
   
 
 0.579
PDE5A
cGMP-specific 3',5'-cyclic phosphodiesterase; Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase catalyzes the specific hydrolysis of cGMP to 5'-GMP. Specifically regulates nitric-oxide-generated cGMP.
   
  
 0.560
ARF5
ADP ribosylation factor 5; Belongs to the small GTPase superfamily. Arf family.
    
  0.538
ARF1
Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.
    
  0.538
ARF4
ADP ribosylation factor 4; Belongs to the small GTPase superfamily. Arf family.
    
  0.538
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.