HSF1 protein (Canis lupus familiaris) - STRING interaction network

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Score

HSF1

Heat shock transcription factor 1. (554 aa)

Predicted Functional Partners:

HSPA1

0.964

HSPBP1

0.944

HSF2

0.927

HSBP1

0.923

HSPA4

0.912

HSPB1

0.892

STUB1

0.889

GSK3B

0.860

FBXW7

0.834

EEF1A1

0.821

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EEF1A1	HSF1	ENSCAFP00000003867	ENSCAFP00000002268	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	Heat shock transcription factor 1.	0.821
EEF1A1	HSPA1	ENSCAFP00000003867	ENSCAFP00000000903	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	Heat shock 70 kDa protein 1; Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis and ADP [...]	0.654
FBXW7	GSK3B	ENSCAFP00000011996	ENSCAFP00000034412	F-box and WD repeat domain containing 7.	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.	0.494
FBXW7	HSF1	ENSCAFP00000011996	ENSCAFP00000002268	F-box and WD repeat domain containing 7.	Heat shock transcription factor 1.	0.834
GSK3B	FBXW7	ENSCAFP00000034412	ENSCAFP00000011996	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.	F-box and WD repeat domain containing 7.	0.494
GSK3B	HSF1	ENSCAFP00000034412	ENSCAFP00000002268	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.	Heat shock transcription factor 1.	0.860
GSK3B	HSPA4	ENSCAFP00000034412	ENSCAFP00000062263	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.	Heat shock 70 kDa protein 4.	0.483
HSBP1	HSF1	ENSCAFP00000029594	ENSCAFP00000002268	Heat shock factor binding protein 1.	Heat shock transcription factor 1.	0.923
HSBP1	HSF2	ENSCAFP00000029594	ENSCAFP00000001385	Heat shock factor binding protein 1.	Heat shock transcription factor 2.	0.499
HSBP1	HSPA1	ENSCAFP00000029594	ENSCAFP00000000903	Heat shock factor binding protein 1.	Heat shock 70 kDa protein 1; Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis and ADP [...]	0.426
HSF1	EEF1A1	ENSCAFP00000002268	ENSCAFP00000003867	Heat shock transcription factor 1.	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	0.821
HSF1	FBXW7	ENSCAFP00000002268	ENSCAFP00000011996	Heat shock transcription factor 1.	F-box and WD repeat domain containing 7.	0.834
HSF1	GSK3B	ENSCAFP00000002268	ENSCAFP00000034412	Heat shock transcription factor 1.	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.	0.860
HSF1	HSBP1	ENSCAFP00000002268	ENSCAFP00000029594	Heat shock transcription factor 1.	Heat shock factor binding protein 1.	0.923
HSF1	HSF2	ENSCAFP00000002268	ENSCAFP00000001385	Heat shock transcription factor 1.	Heat shock transcription factor 2.	0.927
HSF1	HSPA1	ENSCAFP00000002268	ENSCAFP00000000903	Heat shock transcription factor 1.	Heat shock 70 kDa protein 1; Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis and ADP [...]	0.964
HSF1	HSPA4	ENSCAFP00000002268	ENSCAFP00000062263	Heat shock transcription factor 1.	Heat shock 70 kDa protein 4.	0.912
HSF1	HSPB1	ENSCAFP00000002268	ENSCAFP00000019945	Heat shock transcription factor 1.	Heat shock protein beta-1; Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding- competent state. Plays a role in stress resistance and actin organization. Through its molecular chaperone activity may regulate numerous biological processes including the phosphorylation and the axonal transport of neurofilament proteins.	0.892
HSF1	HSPBP1	ENSCAFP00000002268	ENSCAFP00000048479	Heat shock transcription factor 1.	HSPA (Hsp70) binding protein 1.	0.944
HSF1	STUB1	ENSCAFP00000002268	ENSCAFP00000036229	Heat shock transcription factor 1.	STIP1 homology and U-box containing protein 1.	0.889