STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TREML2Triggering receptor expressed on myeloid cells like 2. (480 aa)    
Predicted Functional Partners:
TREM2
Triggering receptor expressed on myeloid cells 2.
 
 
 
 0.809
TREM1
Triggering receptor expressed on myeloid cells 1.
 
 
 
 0.744
INPP5D
Inositol polyphosphate-5-phosphatase D.
    
 
 0.716
DEF8
Differentially expressed in FDCP 8 homolog.
   
  
 0.682
CASS4
Cas scaffold protein family member 4.
      
 0.680
PRSS36
Polyserase-2; Serine protease. Has a preference for substrates with an Arg instead of a Lys residue in position P1. Belongs to the peptidase S1 family.
      
 0.679
PTK2B
Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family.
   
 
 0.657
NFYA
Nuclear transcription factor Y subunit alpha.
      
 0.642
GPR65
G protein-coupled receptor 65; Belongs to the G-protein coupled receptor 1 family.
   
  
 0.610
NCF2
Neutrophil cytosolic factor 2.
   
  
 0.594
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.