STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SLC52A1Uncharacterized protein. (447 aa)    
Predicted Functional Partners:
TCTN2
Tectonic family member 2.
      
 0.783
RTTN
Rotatin.
      
 0.775
SLC9C2
Solute carrier family 9 member C2 (putative).
      
 0.750
SLC22A11
Solute carrier family 22 member 11.
      
 0.749
SNX12
PX domain-containing protein.
    
 
 0.680
SLC25A18
Solute carrier family 25 member 18; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.677
SLC47A1
Multidrug and toxin extrusion protein; Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
      
 0.654
SIAH3
E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
      
 0.647
F1PI31_CANLF
Uncharacterized protein.
    
 
 0.630
SLC22A10
Solute carrier family 22 member 10.
      
 0.623
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.