FOXP4 protein (Canis lupus familiaris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

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Experiments

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[Homology]

Score

FOXP4

Forkhead box P4. (681 aa)

Predicted Functional Partners:

FOXP2

0.933

FOXP3

0.836

AGAP3

0.816

FOXP1

0.790

PCNA

0.692

HAND1

0.666

ZNF609

0.632

DHDDS

0.592

WDR5B

0.580

WDR5

0.580

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGAP3	FOXP4	ENSCAFP00000058004	ENSCAFP00000002320	ArfGAP with GTPase domain, ankyrin repeat and PH domain 3.	Forkhead box P4.	0.816
DHDDS	FOXP4	ENSCAFP00000046970	ENSCAFP00000002320	Alkyl transferase; Belongs to the UPP synthase family.	Forkhead box P4.	0.592
FOXP1	FOXP2	ENSCAFP00000056417	ENSCAFP00000047072	Forkhead box P1.	Forkhead box P2.	0.815
FOXP1	FOXP3	ENSCAFP00000056417	ENSCAFP00000023435	Forkhead box P1.	Forkhead box P3.	0.800
FOXP1	FOXP4	ENSCAFP00000056417	ENSCAFP00000002320	Forkhead box P1.	Forkhead box P4.	0.790
FOXP2	FOXP1	ENSCAFP00000047072	ENSCAFP00000056417	Forkhead box P2.	Forkhead box P1.	0.815
FOXP2	FOXP3	ENSCAFP00000047072	ENSCAFP00000023435	Forkhead box P2.	Forkhead box P3.	0.931
FOXP2	FOXP4	ENSCAFP00000047072	ENSCAFP00000002320	Forkhead box P2.	Forkhead box P4.	0.933
FOXP2	WDR5	ENSCAFP00000047072	ENSCAFP00000065698	Forkhead box P2.	WD repeat domain 5.	0.469
FOXP2	WDR5B	ENSCAFP00000047072	ENSCAFP00000017508	Forkhead box P2.	WD repeat domain 5B.	0.469
FOXP3	FOXP1	ENSCAFP00000023435	ENSCAFP00000056417	Forkhead box P3.	Forkhead box P1.	0.800
FOXP3	FOXP2	ENSCAFP00000023435	ENSCAFP00000047072	Forkhead box P3.	Forkhead box P2.	0.931
FOXP3	FOXP4	ENSCAFP00000023435	ENSCAFP00000002320	Forkhead box P3.	Forkhead box P4.	0.836
FOXP4	AGAP3	ENSCAFP00000002320	ENSCAFP00000058004	Forkhead box P4.	ArfGAP with GTPase domain, ankyrin repeat and PH domain 3.	0.816
FOXP4	DHDDS	ENSCAFP00000002320	ENSCAFP00000046970	Forkhead box P4.	Alkyl transferase; Belongs to the UPP synthase family.	0.592
FOXP4	FOXP1	ENSCAFP00000002320	ENSCAFP00000056417	Forkhead box P4.	Forkhead box P1.	0.790
FOXP4	FOXP2	ENSCAFP00000002320	ENSCAFP00000047072	Forkhead box P4.	Forkhead box P2.	0.933
FOXP4	FOXP3	ENSCAFP00000002320	ENSCAFP00000023435	Forkhead box P4.	Forkhead box P3.	0.836
FOXP4	HAND1	ENSCAFP00000002320	ENSCAFP00000026018	Forkhead box P4.	Heart and neural crest derivatives expressed 1.	0.666
FOXP4	PCNA	ENSCAFP00000002320	ENSCAFP00000009045	Forkhead box P4.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.692