GUCA1A protein (Canis lupus familiaris) - STRING interaction network

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Score

GUCA1A

Guanylate cyclase activator 1A. (205 aa)

Predicted Functional Partners:

GUCA1C

0.962

GUCA1B

0.831

CNGA1

0.811

F1P7U7_CANLF

0.747

ENSCAFP00000056205

0.747

GUCY2D

0.745

GUCY2F

0.745

ENSCAFP00000060510

0.722

GUF1

0.665

LENEP

0.644

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CNGA1	GUCA1A	ENSCAFP00000035274	ENSCAFP00000002385	cGMP-gated cation channel alpha-1; Subunit of the rod cyclic GMP-gated cation channel, which is involved in the final stage of the phototransduction pathway. When light hits rod photoreceptors, cGMP concentrations decrease causing rapid closure of CNGA1/CNGB1 channels and, therefore, hyperpolarization of the membrane potential.	Guanylate cyclase activator 1A.	0.811
CNGA1	GUCA1C	ENSCAFP00000035274	ENSCAFP00000015128	cGMP-gated cation channel alpha-1; Subunit of the rod cyclic GMP-gated cation channel, which is involved in the final stage of the phototransduction pathway. When light hits rod photoreceptors, cGMP concentrations decrease causing rapid closure of CNGA1/CNGB1 channels and, therefore, hyperpolarization of the membrane potential.	Guanylate cyclase activator 1C.	0.848
CNGA1	GUCY2D	ENSCAFP00000035274	ENSCAFP00000024862	cGMP-gated cation channel alpha-1; Subunit of the rod cyclic GMP-gated cation channel, which is involved in the final stage of the phototransduction pathway. When light hits rod photoreceptors, cGMP concentrations decrease causing rapid closure of CNGA1/CNGB1 channels and, therefore, hyperpolarization of the membrane potential.	Retinal guanylyl cyclase 1; Catalyzes the synthesis of cyclic GMP (cGMP) in rods and cones of photoreceptors. Plays an essential role in phototransduction, by mediating cGMP replenishment. May also participate in the trafficking of membrane-associated proteins to the photoreceptor outer segment membrane.	0.404
CNGA1	GUCY2F	ENSCAFP00000035274	ENSCAFP00000026657	cGMP-gated cation channel alpha-1; Subunit of the rod cyclic GMP-gated cation channel, which is involved in the final stage of the phototransduction pathway. When light hits rod photoreceptors, cGMP concentrations decrease causing rapid closure of CNGA1/CNGB1 channels and, therefore, hyperpolarization of the membrane potential.	Guanylate cyclase.	0.461
ENSCAFP00000056205	GUCA1A	ENSCAFP00000056205	ENSCAFP00000002385	Guanylate cyclase domain-containing protein.	Guanylate cyclase activator 1A.	0.747
ENSCAFP00000056205	GUCA1C	ENSCAFP00000056205	ENSCAFP00000015128	Guanylate cyclase domain-containing protein.	Guanylate cyclase activator 1C.	0.683
ENSCAFP00000056205	GUCY2D	ENSCAFP00000056205	ENSCAFP00000024862	Guanylate cyclase domain-containing protein.	Retinal guanylyl cyclase 1; Catalyzes the synthesis of cyclic GMP (cGMP) in rods and cones of photoreceptors. Plays an essential role in phototransduction, by mediating cGMP replenishment. May also participate in the trafficking of membrane-associated proteins to the photoreceptor outer segment membrane.	0.506
ENSCAFP00000056205	GUCY2F	ENSCAFP00000056205	ENSCAFP00000026657	Guanylate cyclase domain-containing protein.	Guanylate cyclase.	0.506
ENSCAFP00000060510	F1P7U7_CANLF	ENSCAFP00000060510	ENSCAFP00000007834	Guanylate cyclase domain-containing protein.	Guanylate cyclase.	0.900
ENSCAFP00000060510	GUCA1A	ENSCAFP00000060510	ENSCAFP00000002385	Guanylate cyclase domain-containing protein.	Guanylate cyclase activator 1A.	0.722
ENSCAFP00000060510	GUCA1C	ENSCAFP00000060510	ENSCAFP00000015128	Guanylate cyclase domain-containing protein.	Guanylate cyclase activator 1C.	0.666
F1P7U7_CANLF	ENSCAFP00000060510	ENSCAFP00000007834	ENSCAFP00000060510	Guanylate cyclase.	Guanylate cyclase domain-containing protein.	0.900
F1P7U7_CANLF	GUCA1A	ENSCAFP00000007834	ENSCAFP00000002385	Guanylate cyclase.	Guanylate cyclase activator 1A.	0.747
F1P7U7_CANLF	GUCA1C	ENSCAFP00000007834	ENSCAFP00000015128	Guanylate cyclase.	Guanylate cyclase activator 1C.	0.683
F1P7U7_CANLF	GUCY2D	ENSCAFP00000007834	ENSCAFP00000024862	Guanylate cyclase.	Retinal guanylyl cyclase 1; Catalyzes the synthesis of cyclic GMP (cGMP) in rods and cones of photoreceptors. Plays an essential role in phototransduction, by mediating cGMP replenishment. May also participate in the trafficking of membrane-associated proteins to the photoreceptor outer segment membrane.	0.506
F1P7U7_CANLF	GUCY2F	ENSCAFP00000007834	ENSCAFP00000026657	Guanylate cyclase.	Guanylate cyclase.	0.506
GUCA1A	CNGA1	ENSCAFP00000002385	ENSCAFP00000035274	Guanylate cyclase activator 1A.	cGMP-gated cation channel alpha-1; Subunit of the rod cyclic GMP-gated cation channel, which is involved in the final stage of the phototransduction pathway. When light hits rod photoreceptors, cGMP concentrations decrease causing rapid closure of CNGA1/CNGB1 channels and, therefore, hyperpolarization of the membrane potential.	0.811
GUCA1A	ENSCAFP00000056205	ENSCAFP00000002385	ENSCAFP00000056205	Guanylate cyclase activator 1A.	Guanylate cyclase domain-containing protein.	0.747
GUCA1A	ENSCAFP00000060510	ENSCAFP00000002385	ENSCAFP00000060510	Guanylate cyclase activator 1A.	Guanylate cyclase domain-containing protein.	0.722
GUCA1A	F1P7U7_CANLF	ENSCAFP00000002385	ENSCAFP00000007834	Guanylate cyclase activator 1A.	Guanylate cyclase.	0.747