STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FOXH1Forkhead box H1. (399 aa)    
Predicted Functional Partners:
SMAD2
Mothers against decapentaplegic homolog.
    
 
 0.881
FBXL6
F-box and leucine rich repeat protein 6.
      
 0.780
SMAD3
Mothers against decapentaplegic homolog.
   
 
 0.766
DRAP1
DR1 associated protein 1.
    
 
 0.698
CER1
Cerberus 1, DAN family BMP antagonist.
      
 0.672
SMAD4
Mothers against decapentaplegic homolog.
    
 
 0.663
PITX2
Paired like homeodomain 2.
    
 
 0.604
NODAL
Nodal growth differentiation factor.
   
  
 0.579
ZBED9
Zinc finger BED-type containing 9.
    
 
 0.538
NKX2-5
Transcription factor NKX2.5.
   
 
 0.527
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.