STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PRUNE2Prune homolog 2 with BCH domain. (3068 aa)    
Predicted Functional Partners:
PRUNE1
Prune exopolyphosphatase 1.
     
 0.834
HDDC3
HD domain containing 3.
     
 0.798
COPZ2
Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.
      
 0.593
OTUD7A
OTU deubiquitinase 7A.
      
 0.592
TM7SF2
Transmembrane 7 superfamily member 2.
      
 0.591
PRDM15
PR/SET domain 15.
      
 0.591
SNX2
Sorting nexin 2.
    
   0.583
APRT
Adenine phosphoribosyltransferase.
     
 0.571
FBXL21
F-box domain-containing protein.
      
 0.546
CDCP2
CUB domain containing protein 2.
      
 0.537
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (26%) [HD]