TRERF1 protein (Canis lupus familiaris) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

TRERF1

Transcriptional regulating factor 1. (1239 aa)

Predicted Functional Partners:

DNTTIP1

0.983

ELMSAN1

0.854

TAF8

0.817

C12H6orf132

0.739

HDAC2

0.707

HDAC1

0.688

CYP39A1

0.642

PTGER4

0.585

ZBTB18

0.584

TXLNA

0.582

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C12H6orf132	PTGER4	ENSCAFP00000043176	ENSCAFP00000046114	Chromosome 12 C6orf132 homolog.	Prostaglandin E receptor 4; Belongs to the G-protein coupled receptor 1 family.	0.508
C12H6orf132	TAF8	ENSCAFP00000043176	ENSCAFP00000002377	Chromosome 12 C6orf132 homolog.	TATA-box binding protein associated factor 8.	0.688
C12H6orf132	TRERF1	ENSCAFP00000043176	ENSCAFP00000002395	Chromosome 12 C6orf132 homolog.	Transcriptional regulating factor 1.	0.739
CYP39A1	TRERF1	ENSCAFP00000052717	ENSCAFP00000002395	Cytochrome P450 family 39 subfamily A member 1; Belongs to the cytochrome P450 family.	Transcriptional regulating factor 1.	0.642
DNTTIP1	ELMSAN1	ENSCAFP00000014289	ENSCAFP00000057968	Deoxynucleotidyltransferase terminal interacting protein 1.	ELM2 and Myb/SANT domain containing 1.	0.976
DNTTIP1	HDAC1	ENSCAFP00000014289	ENSCAFP00000036819	Deoxynucleotidyltransferase terminal interacting protein 1.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.767
DNTTIP1	HDAC2	ENSCAFP00000014289	ENSCAFP00000042408	Deoxynucleotidyltransferase terminal interacting protein 1.	Histone deacetylase 2.	0.724
DNTTIP1	TRERF1	ENSCAFP00000014289	ENSCAFP00000002395	Deoxynucleotidyltransferase terminal interacting protein 1.	Transcriptional regulating factor 1.	0.983
ELMSAN1	DNTTIP1	ENSCAFP00000057968	ENSCAFP00000014289	ELM2 and Myb/SANT domain containing 1.	Deoxynucleotidyltransferase terminal interacting protein 1.	0.976
ELMSAN1	HDAC1	ENSCAFP00000057968	ENSCAFP00000036819	ELM2 and Myb/SANT domain containing 1.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.691
ELMSAN1	HDAC2	ENSCAFP00000057968	ENSCAFP00000042408	ELM2 and Myb/SANT domain containing 1.	Histone deacetylase 2.	0.691
ELMSAN1	TRERF1	ENSCAFP00000057968	ENSCAFP00000002395	ELM2 and Myb/SANT domain containing 1.	Transcriptional regulating factor 1.	0.854
HDAC1	DNTTIP1	ENSCAFP00000036819	ENSCAFP00000014289	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Deoxynucleotidyltransferase terminal interacting protein 1.	0.767
HDAC1	ELMSAN1	ENSCAFP00000036819	ENSCAFP00000057968	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	ELM2 and Myb/SANT domain containing 1.	0.691
HDAC1	HDAC2	ENSCAFP00000036819	ENSCAFP00000042408	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Histone deacetylase 2.	0.980
HDAC1	TRERF1	ENSCAFP00000036819	ENSCAFP00000002395	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	Transcriptional regulating factor 1.	0.688
HDAC2	DNTTIP1	ENSCAFP00000042408	ENSCAFP00000014289	Histone deacetylase 2.	Deoxynucleotidyltransferase terminal interacting protein 1.	0.724
HDAC2	ELMSAN1	ENSCAFP00000042408	ENSCAFP00000057968	Histone deacetylase 2.	ELM2 and Myb/SANT domain containing 1.	0.691
HDAC2	HDAC1	ENSCAFP00000042408	ENSCAFP00000036819	Histone deacetylase 2.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.980
HDAC2	TRERF1	ENSCAFP00000042408	ENSCAFP00000002395	Histone deacetylase 2.	Transcriptional regulating factor 1.	0.707