STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HMOX1Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (288 aa)    
Predicted Functional Partners:
HMOX2
Heme oxygenase 2.
  
 
0.977
BLVRA
Biliverdin reductase A.
     
 0.972
NFE2L2
Nuclear factor, erythroid 2 like 2.
    
 
 0.959
BLVRB
Biliverdin reductase B.
    
 0.944
FECH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.
    
 0.924
FXN
Frataxin.
     
 0.922
KEAP1
Kelch like ECH associated protein 1.
      
 0.906
HEPH
Hephaestin; Belongs to the multicopper oxidase family.
     
 0.905
HEPHL1
Hephaestin like 1; Belongs to the multicopper oxidase family.
     
 0.891
COX10
Cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10.
     
 0.888
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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