STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TOM1Target of myb1 membrane trafficking protein; Belongs to the TOM1 family. (509 aa)    
Predicted Functional Partners:
TOLLIP
Toll interacting protein.
   
 
 0.859
MYO6
Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
    
 
 0.856
CUEDC1
CUE domain containing 1.
    
   0.684
ZFYVE16
Zinc finger FYVE domain-containing protein.
    
 
 0.672
TNFAIP8L2
TNF alpha induced protein 8 like 2.
      
 0.665
DGCR6L
Uncharacterized protein.
   
  
 0.618
LRCH3
Leucine rich repeats and calponin homology domain containing 3.
      
 0.577
URGCP
Upregulator of cell proliferation.
    
   0.575
ANAPC4
Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family.
      
 0.533
STXBP5
Syntaxin binding protein 5.
      
 0.527
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.