STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LARGE1LARGE xylosyl- and glucuronyltransferase 1. (800 aa)    
Predicted Functional Partners:
B4GAT1
Beta-1,4-glucuronyltransferase 1.
  
0.978
RXYLT1
Uncharacterized protein.
  
 
 0.882
LARGE2
LARGE xylosyl- and glucuronyltransferase 2.
     
  0.881
FKRP
Fukutin related protein.
      
 0.806
FKTN
Fukutin.
   
  
 0.799
B3GALNT2
Beta-1,3-N-acetylgalactosaminyltransferase 2.
      
 0.794
DAG1
Alpha-dystroglycan; The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sacrolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization. Beta-dystroglycan is a transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton. Acts as a cell adhesion receptor in both muscle and non- muscle tissues. Receptor for both DMD and UTRN and, through these interactions, scaffolds axin to the cytoskeleton. Also functions in cell ad [...]
   
 
 0.777
POMK
Protein O-mannose kinase.
      
 0.740
CHAMP1
Chromosome alignment maintaining phosphoprotein 1.
      
 0.690
POMGNT1
Protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-).
   
  
 0.685
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.