STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KLHDC3Kelch domain containing 3. (382 aa)    
Predicted Functional Partners:
CUL2
Cullin 2; Belongs to the cullin family.
    
 
 0.947
MOCS1
Molybdenum cofactor synthesis 1.
    
   0.821
ELOB
Elongin B.
    
 
 0.816
UBXN7
UBX domain-containing protein 7.
    
   0.744
RBX1
Ring-box 1.
    
 
 0.743
ELOC
Elongin C; Belongs to the SKP1 family.
    
 
 0.725
ENSCAFP00000054409
Skp1_POZ domain-containing protein.
    
 
 0.725
MEA1
Male-enhanced antigen 1.
      
 0.709
NEDD8
NEDD8 ubiquitin like modifier.
    
 
 0.709
APPBP2
Amyloid beta precursor protein binding protein 2.
      
 0.692
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.