STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PWP1PWP1 homolog, endonuclein. (500 aa)    
Predicted Functional Partners:
RPF2
Ribosome production factor 2 homolog.
   
 
 0.934
BRIX1
Biogenesis of ribosomes BRX1.
   
 
 0.930
EBNA1BP2
EBNA1 binding protein 2.
   
 
 0.922
GRWD1
Glutamate rich WD repeat containing 1.
   
  
0.902
PWP2
Uncharacterized protein.
   
  
 0.901
NOC2L
NOC2 like nucleolar associated transcriptional repressor.
   
 
 0.897
WDR3
WD repeat domain 3.
   
  
 0.889
SDAD1
Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family.
   
  
 0.887
GTPBP4
Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.
   
 
 0.886
RSL24D1
Ribosomal L24 domain containing 1.
   
  
 0.886
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.