STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ANXA1Annexin. (345 aa)    
Predicted Functional Partners:
FPR2
Formyl peptide receptor 2; Belongs to the G-protein coupled receptor 1 family.
    
 0.959
S100A11
Protein S100; Belongs to the S-100 family.
   
 0.931
S100A10
S_100 domain-containing protein; Belongs to the S-100 family.
   
 0.887
ANXA2
Annexin A2; Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response. Inhibits PCSK9-enhanced LDLR degradation, probably reduces PCSK9 protein levels via a translational mechanism but also competes with LDLR for binding with PCSK9; Belongs to the annexin family.
  
 
0.882
S100A5
Protein S100-A4.
   
 0.869
ENSCAFP00000038290
annotation not available
   
 0.854
J9P5V4_CANLF
S_100 domain-containing protein; Belongs to the S-100 family.
   
 0.854
ENSCAFP00000055586
S_100 domain-containing protein; Belongs to the S-100 family.
   
 0.854
LOC100687983
Uncharacterized protein.
   
   0.842
J9P1X3_CANLF
Uncharacterized protein.
   
   0.842
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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