STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
WFS1Wolframin ER transmembrane glycoprotein. (1117 aa)    
Predicted Functional Partners:
TMEM214
Transmembrane protein 214.
   
  
 0.740
SLC26A4
Pendrin; Sodium-independent transporter of chloride and iodide. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
      
 0.706
TMC1
Transmembrane channel-like protein.
    
 
 0.662
ACYP2
Acylphosphatase.
   
  
 0.651
OCIAD2
OCIA domain containing 2.
      
 0.636
CHMP4B
Charged multivesicular body protein 4B.
   
  
 0.609
TMEM126A
Transmembrane protein 126A.
      
 0.597
OTOF
Otoferlin.
      
 0.588
POPDC2
Popeye domain containing 2.
      
 0.569
MYO15A
Myosin XVA.
   
  
 0.567
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.