STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
WFS1Wolframin ER transmembrane glycoprotein. (1117 aa)    
Predicted Functional Partners:
ATF6
Activating transcription factor 6.
   
 0.931
ATF6B
Activating transcription factor 6 beta.
    
 0.912
TMC1
Transmembrane channel-like protein.
    
 
 0.797
CLCA2
Chloride channel accessory 2.
    
 
 0.789
RIC8A
RIC8 guanine nucleotide exchange factor A.
   
    0.724
CISD2
CDGSH iron sulfur domain 2.
      
 0.710
CLIC5
Chloride intracellular channel protein; Belongs to the chloride channel CLIC family.
      
 0.710
ADGRV1
Adhesion G protein-coupled receptor V1; Belongs to the G-protein coupled receptor 2 family.
      
 0.709
STOX1
Storkhead box 1.
      
 0.709
RPGRIP1L
RPGRIP1 like.
      
 0.709
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.