STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RTCBRNA-splicing ligase RtcB homolog; Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs. (505 aa)    
Predicted Functional Partners:
DDX1
DEAD-box helicase 1.
   
 
 0.850
FAM98B
Family with sequence similarity 98 member B.
    
 
 0.841
C10H2orf49
Chromosome 10 C2orf49 homolog.
   
 
 0.821
ZBTB8OS
Zinc finger and BTB domain containing 8 opposite strand.
 
 
 0.781
RTCA
RNA 3'-terminal phosphate cyclase.
  
  
 0.762
MCC
MCC regulator of WNT signaling pathway.
  
  
 0.665
SLFNL1
Schlafen like 1.
   
 
 0.620
RTRAF
Uncharacterized protein.
   
 
 0.612
J9P858_CANLF
Uncharacterized protein.
   
 
 0.612
ENSCAFP00000050486
Uncharacterized protein.
   
 
 0.612
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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