STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PRDM4PR domain zinc finger protein 4; May function as a transcription factor involved in cell differentiation. (801 aa)    
Predicted Functional Partners:
NGFR
Nerve growth factor receptor.
    
 0.883
CHEK2
Tetratricopeptide repeat domain 28.
    
 
 0.799
RBFOX3
RNA binding protein fox-1 homolog 3; RNA-binding protein that regulates alternative splicing events.
    
 
 0.723
SETDB2
SET domain bifurcated histone lysine methyltransferase 2.
   
 0.699
SETDB1
SET domain bifurcated histone lysine methyltransferase 1.
   
 0.673
VIPAS39
VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog.
      
 0.660
SETD4
SET domain containing 4.
   
 0.652
TRMT44
C3H1-type domain-containing protein.
      
 0.629
TRMT13
tRNA methyltransferase 13 homolog.
      
 0.629
CMTR2
Cap methyltransferase 2.
      
 0.629
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.