STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TMC1Transmembrane channel-like protein. (760 aa)    
Predicted Functional Partners:
CIB2
Calcium and integrin binding family member 2.
    
 
 0.864
SLC26A5
Prestin; Motor protein that converts auditory stimuli to length changes in outer hair cells and mediates sound amplification in the mammalian hearing organ; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
    
 
 0.854
TMIE
Transmembrane inner ear.
   
  
 0.853
COCH
Cochlin.
    
 0.828
MYO7A
Myosin VIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
     
 0.813
BAIAP2L2
BAI1 associated protein 2 like 2.
      
 0.811
CDH23
Cadherin related 23.
    
 
 0.810
LHFPL5
LHFPL tetraspan subfamily member 5.
   
 
 0.808
CLIC5
Chloride intracellular channel protein; Belongs to the chloride channel CLIC family.
      
 0.808
WFS1
Wolframin ER transmembrane glycoprotein.
    
 
 0.797
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.