STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DDX58DExD/H-box helicase 58. (925 aa)    
Predicted Functional Partners:
ISG15
ISG15 ubiquitin like modifier.
   
 0.991
DHX58
DExH-box helicase 58.
   
0.984
RNF125
Ring finger protein 125.
    
 0.983
RNF135
Ring finger protein 135.
   
 0.979
TRIM25
Tripartite motif containing 25.
   
 0.957
EIF2AK2
Eukaryotic translation initiation factor 2-alpha kinase 2.
   
 
 0.952
RSAD2
Radical S-adenosyl methionine domain containing 2.
   
  
 0.943
IFI44
Interferon induced protein 44.
   
 
 0.937
TRIM80
Uncharacterized protein.
   
 0.936
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.935
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.