node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C29H8orf37 | RPGR | ENSCAFP00000013873 | ENSCAFP00000037530 | Chromosome 29 C8orf37 homolog. | X-linked retinitis pigmentosa GTPase regulator; Could be a guanine-nucleotide releasing factor. Plays a role in ciliogenesis. Probably regulates cilia formation by regulating actin stress filaments and cell contractility. May be involved in microtubule organization and regulation of transport in primary cilia. Plays an important role in photoreceptor integrity. May play a critical role in spermatogenesis and in intraflagellar transport processes. | 0.639 |
C29H8orf37 | TOPORS | ENSCAFP00000013873 | ENSCAFP00000002635 | Chromosome 29 C8orf37 homolog. | TOP1 binding arginine/serine rich protein. | 0.636 |
IMPDH1 | KLHL7 | ENSCAFP00000002420 | ENSCAFP00000062060 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. | Kelch like family member 7. | 0.553 |
IMPDH1 | PRPF3 | ENSCAFP00000002420 | ENSCAFP00000017399 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. | Pre-mRNA processing factor 3. | 0.645 |
IMPDH1 | PRPF31 | ENSCAFP00000002420 | ENSCAFP00000003947 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. | Nop domain-containing protein. | 0.640 |
IMPDH1 | PRPF8 | ENSCAFP00000002420 | ENSCAFP00000028357 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. | Pre-mRNA processing factor 8. | 0.639 |
IMPDH1 | RP9 | ENSCAFP00000002420 | ENSCAFP00000004710 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. | RP9 pre-mRNA splicing factor. | 0.621 |
IMPDH1 | RPGR | ENSCAFP00000002420 | ENSCAFP00000037530 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. | X-linked retinitis pigmentosa GTPase regulator; Could be a guanine-nucleotide releasing factor. Plays a role in ciliogenesis. Probably regulates cilia formation by regulating actin stress filaments and cell contractility. May be involved in microtubule organization and regulation of transport in primary cilia. Plays an important role in photoreceptor integrity. May play a critical role in spermatogenesis and in intraflagellar transport processes. | 0.537 |
IMPDH1 | TOPORS | ENSCAFP00000002420 | ENSCAFP00000002635 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. | TOP1 binding arginine/serine rich protein. | 0.604 |
KLHL7 | IMPDH1 | ENSCAFP00000062060 | ENSCAFP00000002420 | Kelch like family member 7. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. | 0.553 |
KLHL7 | PRPF3 | ENSCAFP00000062060 | ENSCAFP00000017399 | Kelch like family member 7. | Pre-mRNA processing factor 3. | 0.615 |
KLHL7 | PRPF31 | ENSCAFP00000062060 | ENSCAFP00000003947 | Kelch like family member 7. | Nop domain-containing protein. | 0.622 |
KLHL7 | PRPF8 | ENSCAFP00000062060 | ENSCAFP00000028357 | Kelch like family member 7. | Pre-mRNA processing factor 8. | 0.633 |
KLHL7 | RPGR | ENSCAFP00000062060 | ENSCAFP00000037530 | Kelch like family member 7. | X-linked retinitis pigmentosa GTPase regulator; Could be a guanine-nucleotide releasing factor. Plays a role in ciliogenesis. Probably regulates cilia formation by regulating actin stress filaments and cell contractility. May be involved in microtubule organization and regulation of transport in primary cilia. Plays an important role in photoreceptor integrity. May play a critical role in spermatogenesis and in intraflagellar transport processes. | 0.525 |
KLHL7 | TOPORS | ENSCAFP00000062060 | ENSCAFP00000002635 | Kelch like family member 7. | TOP1 binding arginine/serine rich protein. | 0.718 |
PRPF3 | IMPDH1 | ENSCAFP00000017399 | ENSCAFP00000002420 | Pre-mRNA processing factor 3. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. | 0.645 |
PRPF3 | KLHL7 | ENSCAFP00000017399 | ENSCAFP00000062060 | Pre-mRNA processing factor 3. | Kelch like family member 7. | 0.615 |
PRPF3 | PRPF31 | ENSCAFP00000017399 | ENSCAFP00000003947 | Pre-mRNA processing factor 3. | Nop domain-containing protein. | 0.997 |
PRPF3 | PRPF8 | ENSCAFP00000017399 | ENSCAFP00000028357 | Pre-mRNA processing factor 3. | Pre-mRNA processing factor 8. | 0.997 |
PRPF3 | RP9 | ENSCAFP00000017399 | ENSCAFP00000004710 | Pre-mRNA processing factor 3. | RP9 pre-mRNA splicing factor. | 0.725 |