STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CEMIP2Cell migration inducing hyaluronidase 2. (1383 aa)    
Predicted Functional Partners:
HAS1
Hyaluronan synthase 1.
    
 
 0.698
SHROOM4
Shroom family member 4.
    
 
 0.621
AP2A2
AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]
      
 0.613
HABP4
Hyaluronan binding protein 4.
      
 0.605
ITIH3
Inter-alpha-trypsin inhibitor heavy chain 3.
   
 
 0.601
ITIH1
Inter-alpha-trypsin inhibitor heavy chain 1.
   
 
 0.601
HAS3
Hyaluronan synthase 3.
    
 
 0.575
ITIH2
Inter-alpha-trypsin inhibitor heavy chain 2.
   
 
 0.543
SCP2
Sterol carrier protein 2; Belongs to the thiolase-like superfamily. Thiolase family.
     
 0.502
SMPD3
Sphingomyelin phosphodiesterase 3.
      
 0.499
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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