STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KCTD8Potassium channel tetramerization domain containing 8. (472 aa)    
Predicted Functional Partners:
RIMS4
Regulating synaptic membrane exocytosis 4.
   
  
 0.746
BEND6
BEN domain containing 6.
      
 0.695
RHOBTB1
Rho related BTB domain containing 1.
    
 
 0.633
YIPF7
Protein YIPF.
      
 0.625
BEND4
BEN domain containing 4.
      
 0.622
USP46
Ubiquitin specific peptidase 46; Belongs to the peptidase C19 family.
   
  
 0.615
LRRC66
Leucine rich repeat containing 66.
      
 0.609
PDCL2
Phosducin like 2.
      
 0.605
GABBR2
Gamma-aminobutyric acid type B receptor subunit 2.
    
 
 0.598
GSX2
GS homeobox 2.
      
 0.594
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.