STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DLK2Delta like non-canonical Notch ligand 2. (430 aa)    
Predicted Functional Partners:
KCNQ3
Potassium voltage-gated channel subfamily Q member 3; Belongs to the potassium channel family.
   
 
 0.578
NUP62CL
Nucleoporin 62 C-terminal like.
    
 
 0.538
NKAIN1
Sodium/potassium transporting ATPase interacting 1.
   
  
 0.495
NKAIN2
Sodium/potassium transporting ATPase interacting 2.
   
  
 0.495
SYT10
Synaptotagmin 10.
    
 
 0.472
NPR1
Guanylate cyclase.
    
 
 0.463
KTN1
Kinectin 1.
    
 0.451
SCN1B
Sodium channel subunit beta-1; Regulatory subunit of multiple voltage-gated sodium channel complexes that play important roles in excitable membranes in brain, heart and skeletal muscle. Enhances the presence of the pore-forming alpha subunit at the cell surface and modulates channel gating characteristics and the rate of channel inactivation. Modulates the activity of a variety of pore-forming alpha subunits, such as SCN1A, SCN2A, SCN3A, SCN4A, SCN5A and SCN10A.
   
 
 0.428
GLS
Glutaminase.
      
 0.426
LYPD3
LY6/PLAUR domain containing 3.
    
 
 0.406
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (20%) [HD]