STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TCP11L2T-complex 11 like 2. (518 aa)    
Predicted Functional Partners:
POLR3B
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
    
 0.745
TMEM263
Transmembrane protein 263.
      
 0.727
PRDM4
PR domain zinc finger protein 4; May function as a transcription factor involved in cell differentiation.
   
 
 0.638
FBXO7
F-box protein 7.
   
  
 0.625
MMADHC
Metabolism of cobalamin associated D.
   
  
 0.603
XKRX
XK-related protein.
   
  
 0.592
HAO2
Hydroxyacid oxidase 2.
   
  
 0.567
TMEM234
Transmembrane protein 234.
      
 0.555
CLPTM1
CLPTM1 regulator of GABA type A receptor forward trafficking.
   
  
 0.522
SMG6
SMG6 nonsense mediated mRNA decay factor.
   
  
 0.521
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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