STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CKAP4Cytoskeleton associated protein 4. (596 aa)    
Predicted Functional Partners:
ZDHHC2
Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family.
   
 
 0.834
LOC610540
Pulmonary surfactant-associated protein A; In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air- liquid interface in the alveoli of the mammalian lung and is essential for normal respiration. Enhances the expression of MYO18A/SP-R210 on alveolar macrophages; Belongs to the SFTPA family.
    
 0.756
TMEM214
Transmembrane protein 214.
   
 
 0.735
GOLM1
Golgi membrane protein 1.
  
  
 0.600
RHBDD1
Rhomboid domain containing 1.
    
 
 0.586
TMX4
Thioredoxin related transmembrane protein 4.
   
 
 0.576
RND3
Rho family GTPase 3.
   
 0.560
POPDC2
Popeye domain containing 2.
      
 0.540
FAM20C
FAM20C golgi associated secretory pathway kinase.
    
  0.531
KLHL31
Kelch like family member 31.
      
 0.525
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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